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Allogeneic transplants that are from genetically matched sibling donors offer the best results in ALL. With new techniques, donor bone marrow from unrelated but immunologically similar donors is proving to work as well as those from matched siblings. If the marrow or blood cells used are the person's own, the transplant is called autologous.

Autologous transplants in people with ALL are generally not beneficial, since there is some danger that the cells used may contain tumor cells and the cancer can regrow.

Treatment advances that reduce this risk, however, may make autologous transplantation feasible in people without family donors. The Blood Stem Cell Collection ProcedureSources of CellsStem cells can be obtained either from the donor's:Bone marrow (bone marrow transplantation)Blood (peripheral blood stem cell transplantation) The Transplant ProcedureThe person with ALL is given high-dose chemotherapy with or without radiation -- a treatment known as conditioning.

The point is to inactivate the immune system and to kill any remaining leukemia cells. A few days after treatment, the person is rescued using the stored stem cells, which are administered through a vein. This may take several hours.

EluRyng (Etonogestrel and Ethinyl Estradiol Vaginal Ring)- Multum may EluRyng (Etonogestrel and Ethinyl Estradiol Vaginal Ring)- Multum fever, chills, hives, shortness of breath, or a fall in blood pressure during the procedure.

The person is kept in a protected environment to minimize infection, and the person usually needs blood cell replacement and nutritional support. Side Effects and ComplicationsStem-cell transplantation is a serious and complex procedure that can cause many short- and long-term side effects and complications. If the count is between 500 and 1,000, the child should avoid large groups. If it falls between 200 and 500, the child should stay at home and should see only healthy visitors who have washed their hands vigorously.

Neutrophil counts below 200 indicate that the child is at high risk for infection and should have no visitors. Preventing InfectionIt is very important to take precautions to prevent infection following chemotherapy or transplantation. Guidelines for infection prevention and control include:Discuss EluRyng (Etonogestrel and Ethinyl Estradiol Vaginal Ring)- Multum the doctor what vaccinations are needed and when.

Children with ALL may need reimmunization. In general, it is best to have immunizations prior to chemotherapy and to avoid live virus vaccines during treatment. Be diligent about hand washing and make sure that visitors wash their hands. Alcohol-based hand rubs are best. Avoid eating raw fruits and vegetables. Poultry, meat, fish, eggs, and other foods should be cooked thoroughly. Do not eat foods purchased at salad bars or buffets. In the first few months after the transplant, be sure to eat protein-rich foods to help restore muscle mass and repair cell damage caused by chemotherapy and radiation.

Dental hygiene is very important, including daily Verapamil Hydrochloride (Verelan PM)- FDA and flossing. Use a soft toothbrush to prevent gum bleeding. Schedule regular visits with your dentist. Do not sleep with pets. Avoid contact with pets' excrement. Avoid fresh flowers and plants as they may carry mold.

Swimming may increase exposure to infection. If you swim, do not submerge your face in water.

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